Pharmaceutical wallets

Ecobliss present at Pharmapack Europe

On 11 & 12 february 2015 Ecobliss will be presenting their solutions in Pharmaceutical packaging

In the Pharmaceutical world there are many different packaging designs and functions. Patient compliance and child resistant packaging are two of the main focus areas. In these areas Ecobliss offers various packaging solutions like ‘blister wallets’ or reclosable child resistant packaging (Locked4Kids). All of these solutions will be presented at Pharmapack Europein Paris Expo Porte De Versailles (Hall 5), stand 122.

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Ecobliss: a smart source for pharmaceutical innovations

Speaking to Printweek, a leading print and packaging magazine Chakravarthi AVPS felt “Today, secondary packaging is being treated as an avoidable burden at all levels, right from the manufacturer to the retailer. Yet the carded blisters and dose pack wallets, apart from the regulated dispenser packs, play a major role in the patients’ convenience and sometimes save the user from potential dangers like consumption of excessive or less dosage, using an expired medicine and so on. Ecobliss continues to drive the necessity of having proper secondary packaging for all the dosage drugs”.

Ramu Ramanathan | Jan 19, 2014

Hyderabad-based Ecobliss highlighted smart innovations in blister packaging at its stall at Indpack. This included a host of packaging options offered by Ecobliss like carded blister packs, dose packs, clinical wallets, promotional packs, drug combination packs, pre-filled syringe packs, innovative vial packs, standy blister packs, etc.


AVPS Chakravarthi, managing director of Ecobliss India, said, “Blister packs have been associated with the pharmaceutical segment due to their convenience, affordability and ease-of-use.” Having said that, one has however, seen little innovation. Ecobliss has disrupted this mould with its ‘Easy opening’ blister packs with special focus on elderly customers.” Chakravarthi added, “The pharmaceutical field is highly demanding when compared with other sectors. One needs to be literally on his toes to constantly serve satisfaction to the customer. We need to update the technologies on real-time basis. In addition, we need to supply packaging for a highly complex US and regulatory market sales at affordable prices, not compromising on quality.”

Products for the elderly
During a product demo to Rushikesh Aravakar and Ramu Ramanathan of PrintWeek India, Chakravarthi explained, “Blister packs are either face heat seal carded packs or clamshell packs. In case of face seal packs, when the customer tries to remove the blister, either part of the plastic remains with the board or some paper remains with the plastic. In case of clamshell blisters it is difficult to tear open; especially for the elderly and infirm. One has to use scissors to cut the pack. Imagine the plight of an elderly person unable to access a special toothbrush from a nice blister pack and who may discard the product without using it.”

He added, “Many customers look at blister packaging in a negative way because of the difficult and unpleasant method of opening. There is a strong need for a blister pack which is sturdy enough to protect the product, as well as be easy to open.” He felt Ecobliss packaging has resolved these issues.

Customer-friendly blister packages
Chakravarthi laid great stress on customer-friendly blister packages. Once again, he demonstrated a new design for a toothbrush with an easy-to-open blister package. The design is simple, a blister presenting the product, encased by a printed cardboard card. After folding back the cardboard card, the customer can simply slide out the blister and access the product. Finally, no more cuts and puncture wounds due to jagged edges, it’s really as simple as 1 2 3.

Chakravarthi explained, “Let us take an example of the complete packaging you need to meet certain requirements. Say that it must protect the contents from tampering, and that the packaging must be tear-resistant and have a metallic finish. Say it needs to be produced in high volumes, preferably in-house, where you will be able to tightly control production scheduling. At Ecobliss, we understand all the component options, all the process possibilities and all the ways to optimise production cost factors to deliver what you need.

A solution for the wallet
In this sense, the wallet solution for the pharma industry is a very innovative concept. Herein, Ecobliss provides blister wallets in many different types and sizes, with one, two, three or more panels designed to match the customer’s requirements. These extra panels can be used to accommodate extra strips with tablets or to print additional information about the content of the wallet. It is even possible to apply a booklet with multiple pages of information onto one of the panels of a blister wallet so that crucial information never gets lost and stays with the medication.

Chakravarthi showed the PrintWeek India duo, a couple of samples and pointed out, “Blister wallets offer many possibilities to accommodate your requirements and the possibilities are endless. Electronics for instance, can be integrated into a wallet for measuring patient compliance, or a wallet can be made child-resistant by design or by applying a child resistant label.”

He explained, “Today, secondary packaging is being treated as an avoidable burden at all levels, right from the manufacturer to the retailer. Yet the carded blisters and dose pack wallets, apart from the regulated dispenser packs, play a major role in the patients’ convenience and sometimes save the user from potential dangers like consumption of excessive or less dosage, using an expired medicine and so on. Ecobliss continues to drive the necessity of having proper secondary packaging for all the dosage drugs in domestic markets as well.”

About Ecobliss
Ecobliss, a global leader in blister and high-visibility packaging, is a privately held company with some 300 staff, and a growing international network of business partners. Ecobliss in India is based in Hyderabad with a sheetfed operation that is backed by finishing solutions. Slowly, but surely, Ecobliss India has become synonymous with know-how and innovation in the specialised field of blister and high-visibility packaging.

It all began in 1995, when Ron Linssen, the founder of Ecobliss, (along with Professor G. Wouters), developed the cold sealing technology for blister packaging, which is the USP of the company’s success. Since the introduction of this eco-friendly sealing technology, customers from many industries have changed their packaging to this method of packaging.

Through the success of cold seal packaging, Ecobliss has become a known name in the market. With many years of experience in development, design, production and logistics, Ecobliss is recognised to be the ‘smart source’ for blister and high-visibility packaging.

Chakravarthi said, “Whether we use blister packaging, plastic boxes or combination of these, regardless of the equipment needed, the intention is always the same: a complete packaging product that meets the highest standards of performance for the lowest cost. At Ecobliss, we design from scratch so that all components are in harmony with each other and any potential logistical challenges are pre-solved.”


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Pharmapack Europe 2014 – A new impulse towards internationalisation

The 13th edition of Pharmapack Europe will be held for the first time in Paris Expo, Porte de Versailles on 12-13 February 2014.

Exhibition: A complete array of specialized and global suppliers
Pharmapack Europe 2014 will host, in this new venue, over 320 exhibitors from over 70 countries offering a wide range of skills that cover the entire supply chain for health product packaging and drug delivery systems.

Conferences: “All about compliance and Security”
The programme of the 2014 edition will have as red thread a highly topical issue of major importance: compliance and security. For two days, the conferences led by leading experts will address the latest trends, technological advances and innovations in drug packaging and delivery systems that can improve compliance, facilitate the administration of the treatments, or further enhance the safety of patients and caregivers.

New! An innovation Gallery showcasing the lastest innovations 
New feature of this edition : The Innovation Gallery. This space will concentrate the latest innovations presented by exhibitors, thus companies will be offered the opportunity to enhance the exposure of their latest developments and new products.

Technical Symposium focused on the latest “Serialization and Track & Trace” issues.
This year, the Technical Symposium returns with a full day dedicated to “Serialization, Track & Trace. How to understand and deploy all aspects of Track & Trace in the pharmaceutical industry.”, a major issue of the 2013-2014 agenda. The presentations and round tables will enable participants to exchange with top experts on their own problematic.


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Medical packaging growing globally

World demand for medical device packaging is projected to increase 5.9 per cent annually to US$25.7bn in 2017, according a new report by Freedonia.

It says that Western Europe, the US and Japan will continue to account for almost 60 per cent of the total market.However, demand in these countries will expand below the average global pace as intensifying health care cost containment pressures and fierce multiple supplier competition weaken growth.

The report predicts the fastest expanding medical device packaging markets will emerge in India, Mexico, China, and the more prosperous Africa and Middle-East countries, where diversification, expansion, and stricter regulation of medical product industries are raising the quality and functional requirements of containers and related accessories.

Freedonia believes that pouches and trays will continue to lead sales among container types based on adaptability to cost effective infection-resistant and security-enhanced formats.

It says that multiple compartment trays will build sales as they virtually eliminate the risk of staff errors and the spread of infectious agents during the preparation of products for surgery and various other patient procedures, adding that clamshell packs will also fare well in the global marketplace as they match or exceed all the advantages of rigid trays while offering greater protection against product damage during transport and storage.

Bags and boxes will realise below average gains in demand. The report says that increasing use in contact lens packaging will boost the market for blister packs.


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Complete wallet solutions for pharmaceutical industry

There are numerous innovations and solutions when it comes to the functionality of pharmaceutical wallet packaging and because there are a lot of them, you might not see the forest for the trees. So how do you know which options to choose? Well at Ecobliss they have made it easy for you! On their website you will find a complete view on different possibilities for medical wallet design together with some video animations which illustrate the different possibilities.

Ecobliss provides blister wallets in many different types and sizes, with one, two, three or more panels always designed to match your requirements. These extra panels can be used to accommodate extra strips with tablets or to print additional information about the content of the wallet. It is even possible to apply a booklet with multiple pages of information onto one of the panels of a blister wallet so crucial information will never get lost and stays with the medication.

Blister wallets offer many possibilities to accommodate your requirements and the possibilities are endless. Electronics for instance, can be integrated into a wallet for measuring patient compliance, or a wallet can be made child resistant by design or by applying a child resistant label. And even if you need an entirely new function, you can count on Ecobliss to be the ‘Smart Source’ for your packaging.

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Ecobliss Pharma website restyled to “The Smart Source”!

Ecobliss has undergone a complete restyling of its corporate identity, combined with a renewed positioning as ‘The Smart Source’ for blister and high visibility packaging. One of the key branches on which Ecobliss is active is pharmaceutical and healthcare industry. With the launch of the website, Ecobliss caters for everyone to visit a website dedicated for this branch. Complete packaging, packaging components and all related equipment can conveniently be viewed. The products and services offered by Ecobliss are embedded in the three step business model of Development, Realization, Implementation which has been the basis of many strong relations Ecobliss has with its customers. If you happen to be active in the pharmaceutical and healthcare business, checking the website is highly recommended.


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Modern Packaging & Design – In conversation with A V P S Chakravarthi

Managing Director of Ecobliss India Pvt Ltd, Mr. A V P S Chakravarthi, gives his perspective on the Indian Pharmaceutical Packaging Industry in an interview with Modern Packaging & Design.

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Child resistant packaging, Definitely not child’s play!

Child resistant packaging, Definitely not child’s play!

Child resistant Packaging Children are naturally attracted to brightly coloured medication and it only takes a second to pop a pill, but this innocent act could lead to tragedy. Child resistant packaging is one optimum solution to this situation. Usha Sharma traces a new trend in the industry.

 Pharma industry needs reliable and speedy packaging solutions that can deliver a combination of product protection, quality, tamper evidence, patient comfort and security requirements. Meeting all these challenges child-resistant (CR) packaging, is designed or constructed to be significantly difficult for children under five years of age to open within a reasonable time but not difficult for normal adults. Such packaging is called child-resistant, rather than childproof, because some children will be able to open it. US and Korean regulatory bodies have already enforced CR packaging guidelines for all pharma products, while efforts are on in the European Union (EU) to develop unified standards across the EU countries .

Avinash Mandale

Avinash Mandale, Global Chief Marketing Officer Bilcare

Avinash Mandale, Global Chief, Marketing Officer Bilcare explains CR packaging’s vital need saying, “CR packaging is essential from the children’s safety angle. Every pharma product needs to be CR packed because it can prevent a child from accidental consumption or misuse of the medicine. For example; if the patient is suffering from diabetes there are chances that his son/daughter may accidentally consume diabetes pills and their sugar level may go down which can lead to a fatal situation.”

In India few leading pharma companies like; Ranbaxy, Cipla, Dr Reddy’s Laboratories, Lupin, USV Wockhardt, Ipca Laboratories, Aurobindo, Strides Arcolab, Indoco Remedies etc, are already using CR packaging but it is mainly meant for generic export markets.


Giving the rationale for the increasing need for CR packaging, Ranjit Shahani, Vice Chairman and Managing Director, Novartis India, reasons that, “CR caps are mandatory for most products in US. Generic players in India, into export to US have to use CR caps with high density polyethylene (HDPE) containers and as US generic drugs markets have shown very good growth compared to other branded drugs, the potential is very vast.”


Debdeep Bhattacharya, Director Ess Dee Aluminium

CP packaging is often available in the form of Ecobliss wallet packs with dose guard labels, CR caps and closures, few customised and tailor-made packs and so on. Normally, the standard CR pill boxes remind the patient to take the medicine at right time. However, the usage of such pill boxes is limited as the medication is transferred from the primary pack to such pill boxes as per the requirement. While designing a CR pack to suit requirements, the challenge lies in commercial production of high volumes at high speeds. Presently, the most common CR packaging available is known as ‘push through’, which needs higher effort to take out the medicine and thus a child would most probably give up after a few attempts. Conventionally, foil available in the market is peelable foil. In a ‘peel and push packaging’ the tablets need to be pushed. However, these two foils are not senior friendly either.The lidding material has a peelable coating and is sealed to the blister using heat and pressure. The packaging and its contents can then be sterilised. Lidding material can be die- cut in any shape required. These materials are compatible with common sterilisation methods such as ethylene oxide (ETO), gamma ray sterilisation, beta ray sterilisation and steam sterilisation. Stressing on the uses of CR foils, Debdeep Bhattacharya, Director, Ess Dee Aluminium says, “CR lidding means safety, security and convenience in preventing children from gaining access to medication. As regulations come into effect, it is important to increase the barriers for children, while simultaneously allowing easy access for seniors.”


In the USA, CR packaging is result of the Poison Prevention Act (PPA) passed by the US Congress in 1970. The purpose of the law is to decrease the opportunity of children to gain access to substances, resulting in accidental poisoning. In addition, the PPA extends to all states or localities in the USA and is the one standard applied for all applicable products. The European standard only covers packages containing paracetamol, aspirin and medicines which containing 24 mg of iron.

 Commenting on CR packaging regulation Bhattacharya says, “US and European testing methodologies are not very different but there are substantial differences in the additional requirements and criteria. US drugs need to be labelled CR, including determination that if ingested by a child, the drug toxicity level would not cause harm or injury. This is not a consideration in determining the type of package used in Europe.”

He further highlights that, “In the US, protocol testing methods were developed primarily to address cap-and-vial closures as this was the preferred packaging format in the 1970s with unit dose formats being virtually non-existent. Today, there is a significant bias towards unit dose formats such a blister and strip packaging. During the protocol development era, it has been estimated that blister use and unit of use packaging formats represented less than 20 per cent of US drug packaging.”


Chakravarthi AVPS, Managing director Ecobliss India Pvt Ltd

Highlighting global CR packaging trends, AVPS Chakravarthi, Managing Director, Ecobliss India says, “Currently legislation exists for commercial products in Europe for UK, Germany and Italy and the Netherlands. The US is the biggest market with extensive legislation and potential litigation. On the clinical trial front all US trials have to use trial samples with CR packaging, but there is no requirement elsewhere in the world.”Commenting on mandatory guideline of CR packaging in India, Mandale says that, “The US and Korea regulatory body has already made it a compulsion and very soon other regions will follow. In India, I assume that it will take some more time to come in force. It would be better if pharma industry does follow the guideline; but I am assuming that it will take some more time to come as an Act and become a regulatory compulsion on each pharma company. Whereas, in the European market regulatory body’s discussions are on going.”



Bharat Mehta, Managing Director Super Label Manufacturing

 ”If Government is looking from safety point of view of child by preventing accidental use of tablets, then it must be mandatory. It should make it mandatory in India as well, for all formulations harmful for children,” says Bharat Mehta, Managing Director, Super Label Manufacturing.





Preferred solution

CR market is growing with more and more companies developing packaging solutions. As arthritic patients find bottles difficult to open, blister packs with thicker foil or paper/foil laminates are also very difficult for such adult patients to access. Also, these are cumbersome, size limiting and expensive. Ecobliss Pharmaceutical wallets clinicalsupported by dose guard and dose guard labels applied directly onto the blisters provide the best cost effective compliance solution and it is for blisters which have the advantage of excellent CR and senior friendly access. The regular Alu-Alu or blister packs are the ones mostly in general use. Chakravarthi enlarges the usage of CR and its cost effective ways saying, “The CR packaging needs to be cost effective and should not add too much to the packaging cost while complying with requirement. And it should be feasible at high volumes and high productions speeds as well.”









Eric Souberiran, Business Managing Director Rexam Pharma Packaging

“Alu-Alu packaging would be confined to a smaller quantity of products and service a niche segment. The need of the hour is to facilitate bulk packaging to reduce costs in the generic market which is being achieved through the use of HDPE containers fitted with CRC caps, observes Eric Souberiran, Business Managing Director, Rexam Pharma Packaging India.

 On the cost front, Mehta says, “To change from current mode of packaging to CR packaging, one needs to understand the advantage as against cost. Indian pharma industry is still quite driven by cost. Normally, the price difference between a product using CR packaging a product normal packaging is a reasonably big difference but depending on size and volume of the products.”

 ”It is a new trend seen in the industry and is emerging differentially. The key reason is to differentiate from other packaging, which is happening in the Indian pharma industry. Indian pharma players are realising that packaging differentiation will make them stand out in the competitive market. And CR packaging will be good for differentiating. I see big pharma giants protecting their brand concealing with CR packaging and these can help the pharma companies to differentiate themselves from their competitor,” analyses Mandale. “The price difference in CR packaging is minor compared to the safety gains.” adds Souberiran. Shahani opines that export oriented Indian pharma companies have implemented CR packaging, but the concept remains underdeveloped in the local markets.

Reaching globally

 Many Indian pharma companies are currently exporting their generic drugs to the US or those planning will have to essentially look at bulk packaging, while, keeping in mind the US FDA regulations. “In the near future, Indian pharma companies are going to be strong contenders in the US generic market, which would necessitate use of CR caps. This coupled with the fact that the pharma consumer in India will also evolve over a period of time makes it necessary for them to pursue this packaging trend. HDPE containers with CRC caps are a perfect fit to meet the demands of this market. So the trend is very positive and we see more and more companies adopting this packing in future,” avers Souberiran.

Suggesting a user friendly point of view, Mandale comments that, “The existing leading foil should evolve into a new form of design solution, which can be provided as a CR pack. The future trend is that CR packaging should be senior friendly, eco friendly and cost effective as well.”

 Chakravarthi sum up the potential when he predicts that, “We see this market (CR) expanding from the US across the world as soon as a cost effective solution is provided.”

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Reckitt Benckiser Healthcare (UK) Ltd, uses Ecobliss cold seal wallets for their clinical trials

Reckitt Benckiser Healthcare (UK) Ltd – Ecobliss Website Case Study

Reckitt Benckiser, the largest pharmaceutical and healthcare company in the Netherlands, has adopted the Ecobliss cold-seal packaging system for a clinical trial of one of their market leading medicinal brands.

reckitt-benckiser wallet

The healthcare facility, based in Hull, UK, has invested in a desktop Ecobliss Jiggle Roller (EJR) 350/500 machine to manually seal their blister packs into cold-seal wallet cards – which are also supplied by Ecobliss Pharma.

It is the first time Reckitt Benckiser have utilised Ecobliss cold-seal technology, which allows for improved efficiency, speed and flexibility in their product packing process.

reckitt-benckiser wallet 2

Furthermore, the simplicity and the compact design of the finished wallet pack (pictured) offers the patient ease-of-use and portability – two vital factors in ensuring the stated dosage is taken and completed correctly.

This clinical study is to be sent to the USA, which means as a legal requirement, the packaging will need to be in certified child resistant packaging. To aid compliance, Ecobliss Pharma – supported by GP Solutions (UK) Ltd – will provide the wallet card with a Dose GuardTM Peel & Push child resistant senior friendly (CRSF) secondary barrier pre-applied on the back. Dose GuardTM is approved to an F4 CR rating; however, developments are currently in place in order for it to achieve F1 status.

To complete delivery of all the packaging components required for this study, GP Solutions will also supply Reckitt Benckiser with tamper evident labels and outer cartons.

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Sanofi-Aventis prepared for cold seal wallet packaging

sanofi-aventis rotary wallet packaging machine

Sanofi-Aventis, one of the world’s leading pharmaceutical companies is preparing for the partial transfer of heat sealing to Ecobliss cold seal packaging.
The R&D facility of Sanofi-Aventis in Montpellier (France) has recently expanded with a brand new facility designated for clinical trial activities. The Sanofi clinical trial packaging service, an innovation oriented entity, is constantly improving its processes for a high degree of quality and flexibility, and will be equipped with five Ecobliss ERP 350/450+ machines.
This type of equipment is designed for perfectly sealing Ecobliss cold seal wallets as well as heat sealing wallets.
Cold sealing and heat sealing in one machine, yet another proof of the ingenuity of Ecobliss Equipment!
The first of the five machines has been successfully installed in September 2008, the remaining ones have been supplied in the course of 2009.

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Dose Guard Child resistance Solutions for Pharmaceutical wallets

Dose Guard Child resistance Solutions for Pharmaceutical wallets

GP Solutions (UK) Ltd has developed a patented and proven technology, which provides child resistance and senior friendly compliance to the new European Standard – ISO EN 14375 for non-recloseable pharmaceutical packaging.

The product, Dose Guard™, is a self-adhesive barrier that utilises a unique “peel & push” mechanism to allow controlled access to each tablet. Dose Guard™ is suitable for application directly onto pharmaceutical wallets.

The combination of multi-part adhesive patterns and die-cutting technology provides child resistance and senior friendliness for most blister pack formats. This is without the need for re-tooling and expensive time consuming stability studies that would be associated with changing the blister contact materials.

GP Solutions Website

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